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Do cardiometabolic diseases increase the risk of dementia?

Do cardiometabolic diseases increase the risk of dementia?

The cardiometabolic diseases were independently associated with the risk of dementia and visible brain imaging differences far more than was a genetic risk.

Agnieszka Szmitkowska, Ph.D.
Jun 23, 2022
News
Social stress accelerates immune aging

Social stress accelerates immune aging

Psychosocial stress potentially contributes to accelerated immune aging. This is important because immune aging plays a role in multiple chronic conditions and the aging process itself.

Ehab Naim, MBA.
Jun 22, 2022
News
Clonal dynamics: A potential contributor to aging and longevity

Clonal dynamics: A potential contributor to aging and longevity

When a hematopoietic stem cell starts making copies with the same genetic mutation, molecular damage accumulates. This causes abrupt changes in tissue composition due to clonal structure alterations.

Ehab Naim, MBA.
Jun 11, 2022

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Article
Berberine: Promoting longevity by boosting the AMPK pathway
Metabolism
Aging
Body
Nutrition
Disease

Berberine: Promoting longevity by boosting the AMPK pathway

This compound has been found to possess several properties, including anti-inflammatory, anticancer, and broad-spectrum antimicrobial activity

Ehab Naim, MBA.
Jun 26, 2022
Article
Article
Twenty-six physiological parameters to assess aging
Diagnostics
Lifestyle
Interventions
Body
Disease

Twenty-six physiological parameters to assess aging

The aging process causes a decline in the overall body function. There are physiological parameters that could help establish how far aging has impacted the body to capture these changes.

Ehab Naim, MBA.
Jun 26, 2022
Article
Article
How Can the DASH Diet Improve longevity?
Nutrition
Lifestyle
Disease
Longevity
Prevention

How Can the DASH Diet Improve longevity?

The DASH diet can be a good choice for those interested in healthy aging and longevity but it is a relatively restrictive diet that can be hard to stick to long-term.

Jiří Kaloč
Jun 26, 2022
Article
Article
Fisetin: A natural senotherapeutic with potent antioxidant properties against aging
Pharmaceuticals
Longevity
Supplements
Metabolism
Aging

Fisetin: A natural senotherapeutic with potent antioxidant properties against aging

Fisetin, a bioactive compound found in edible plants, is reported to have a number of biological activities, including antioxidant, antimicrobial, anticancer, antidiabetic, and other properties

Ehab Naim, MBA.
Jun 25, 2022
News
News
Do cardiometabolic diseases increase the risk of dementia?
Disease
Diagnostics

Do cardiometabolic diseases increase the risk of dementia?

The cardiometabolic diseases were independently associated with the risk of dementia and visible brain imaging differences far more than was a genetic risk.

Agnieszka Szmitkowska, Ph.D.
Jun 23, 2022
Article
Article
Could you predict your brain health? An interview with Owen Phillips Ph.D. founder of BrainKey
Longevity
Diagnostics
Aging
Disease
Lifestyle

Could you predict your brain health? An interview with Owen Phillips Ph.D. founder of BrainKey

Dr. Owen Phillips is a neuroscientist and a founder and CEO of BrainKey – an AI and neuroscience startup. We spoke about neuroscience, aging, and the brain's longevity.

Owen Phillips, Ph.D.
Jun 23, 2022
News
News
Social stress accelerates immune aging
Aging
Lifestyle
Prevention
Body
Longevity

Social stress accelerates immune aging

Psychosocial stress potentially contributes to accelerated immune aging. This is important because immune aging plays a role in multiple chronic conditions and the aging process itself.

Ehab Naim, MBA.
Jun 22, 2022
Article
Article
Nicotinamide mononucleotide: A critical player in aging and longevity
Pharmaceuticals
Supplements
Metabolism
Longevity
Aging

Nicotinamide mononucleotide: A critical player in aging and longevity

Nicotinamide mononucleotide (NMN) is a direct precursor to NAD+, a critical coenzyme found in every cell in your that is involved in hundreds of metabolic processes and its levels decline with age.

Ehab Naim, MBA.
Jun 22, 2022
Article
Article
J147: the next step in disease-modifying therapy for Alzheimer’s?
Aging
Disease
Body
Diagnostics
Pharmaceuticals

J147: the next step in disease-modifying therapy for Alzheimer’s?

‍J147 is a promising drug candidate against Alzheimer’s disease – an illness that affects millions but still lacks reliable therapeutics. ‍J147 may also acts as geroprotector.

Olena Mokshyna, PhD.
Jun 20, 2022
News
News
Clonal dynamics: A potential contributor to aging and longevity
Aging
Longevity
Interventions
Disease
Diagnostics

Clonal dynamics: A potential contributor to aging and longevity

When a hematopoietic stem cell starts making copies with the same genetic mutation, molecular damage accumulates. This causes abrupt changes in tissue composition due to clonal structure alterations.

Ehab Naim, MBA.
Jun 11, 2022
Article
Article
Proteins, fiber, and lipids: Age-proof the gut with diet
Body
Disease
Nutrition
Metabolism
Lifestyle

Proteins, fiber, and lipids: Age-proof the gut with diet

As individuals age, the GIT function and structure begin to deteriorate. These adverse effects could be attenuated by utilizing approaches like controlling dietary components to promote gut health.

Ehab Naim, MBA.
Jun 11, 2022
Article
Article
Empower clients to nurture relationships
Prevention
Disease
Technology
Lifestyle
Aging

Empower clients to nurture relationships

By empowering clients and patients to nurture their relationships, there may be an untapped opportunity to support them with their health and well-being.

Jihane Farrell, Ph.D.
Jun 11, 2022
Video
Video
Genome wide association studies (GWAS)
Aging
Diagnostics
Medicine

Genome wide association studies (GWAS)

Genome-wide association studies help us identify potential causal regions associated with different diseases and potential genetic explanations for the cause of aging.

Eleanor Sheekey
Jun 11, 2022
News
News
How can mindfulness meditation help breast cancer patients?
Disease
Lifestyle
Interventions
Aging
Prevention

How can mindfulness meditation help breast cancer patients?

Mindfulness-based stress reduction can help patients with breast cancer with their mental well-being.

Olena Mokshyna, PhD.
Jun 11, 2022
Article
Article
Should you Eat More Fiber for Longevity?
Nutrition
Lifestyle
Body
Longevity
Disease

Should you Eat More Fiber for Longevity?

Increasing fiber intake to at least 25 g per day correlates with a significant reduction in mortality and risk for chronic disease

Jiří Kaloč
Jun 5, 2022
Article
Article
How to Add Meaning to Your Longevity Exercise Routine
Longevity
Prevention
Lifestyle
Interventions
Body

How to Add Meaning to Your Longevity Exercise Routine

Showing clients how their exercise routines today can impact the desirable outcomes in older age can be a powerful tool for promoting longevity.

Jiří Kaloč
Jun 5, 2022
Video
Video
Are Klotho proteins important for longevity?
Longevity
Metabolism
Nutrition
Interventions
Aging

Are Klotho proteins important for longevity?

What are Klotho proteins, what they do, what evidence links them with longevity? What are potential ways in which restoring Klotho protein levels could be beneficial?

Eleanor Sheekey
Jun 5, 2022
News
News
Type 2 diabetes potentially accelerates brain aging 
Disease
Aging
Medicine
Body

Type 2 diabetes potentially accelerates brain aging 

The executive function, processing speed, and gray matter decrease in patients with type 2 diabetes mellitus.

Ehab Naim, MBA.
Jun 5, 2022
News
News
Which hallmarks of aging does epigenetic age reflect?
Aging
Diagnostics
Longevity
Prevention

Which hallmarks of aging does epigenetic age reflect?

Nutrient sensing, mitochondrial function, stem cell exhaustion, and altered cell-cell communication significantly affect epigenetic aging

Olena Mokshyna, PhD.
Jun 5, 2022
Video
Video
Cellular senescence: role in cancer and aging (Webinar with Eleanor Sheekey recording)
HealthyLongevity.guide
Aging
Body
Interventions
Longevity

Cellular senescence: role in cancer and aging (Webinar with Eleanor Sheekey recording)

Cellular senescence is one of the nine aging hallmarks with the negative impact but also with good aspects, including wound healing, fibrotic tissue resolution, limb patterning...

Ehab Naim, MBA.
Jun 3, 2022
Article
Article
Alzheimer's disease – is there hope?
Aging
Disease
Body
Diagnostics

Alzheimer's disease – is there hope?

Alzheimer's disease (AD) is a debilitating neurodegenerative condition causing cognitive and psychiatric problems. Diagnosis is complicated, and no disease-modifying therapy is available at the moment

Olena Mokshyna, PhD.
Jun 1, 2022
News
News
Urolithin A improves physical performance and mitophagy in middle-aged adults
Nutrition
Supplements
Body
Metabolism

Urolithin A improves physical performance and mitophagy in middle-aged adults

The data showed significant improvement in muscle strength (especially leg muscle strength) at both doses.

Olena Mokshyna, PhD.
Jun 1, 2022
News
News
Telomere attrition is linked to modifiable lifestyle factors
Aging
Metabolism
Longevity
Lifestyle
Prevention

Telomere attrition is linked to modifiable lifestyle factors

Healthy behaviors and modifiable characteristics could potentially influence leukocyte telomere length that is associated with longevity, and age-related diseases.

Ehab Naim, MBA.
Jun 1, 2022
Article
Article
Telomere attrition: a potential limit to longevity?
Aging
Metabolism
Longevity
Prevention
Diagnostics

Telomere attrition: a potential limit to longevity?

Telomere shortening is itself a cause of aging, but telomeres also shorten in response to stresses and diseases. Extending telomeres in animals prolongs their lifespan, albeit modestly.

Victor Björk
May 24, 2022
News
News
Sperm epigenetic age influences pregnancy outcomes
Diagnostics
Aging
Metabolism

Sperm epigenetic age influences pregnancy outcomes

Results revealed that increased sperm epigenetic age (SEA) was associated with a lower probability of achieving pregnancy within 3, 6, and 12 months of trying.

Ehab Naim, MBA.
May 22, 2022
Article
Article
Brain health paves the way to healthy aging and longevity
Body
Longevity
Aging
Disease
Medicine

Brain health paves the way to healthy aging and longevity

Brain health is crucially important for every aspect of our life. Aging changes can be counteracted by lifestyle changes, helping to sustain brain health for longer.

Olena Mokshyna, PhD.
May 22, 2022
Article
Article
The 3 rules of the Okinawa diet for longevity
Nutrition
Lifestyle
Longevity
Prevention
Pharmaceuticals

The 3 rules of the Okinawa diet for longevity

There are several key aspects of the traditional Okinawa diet that can be connected to health and longevity: calorie restriction, high antioxidants intake, low sugar and fat intake.

Jiří Kaloč
May 21, 2022
Video
Video
Harnessing the power of social connections for your client’s longevity - Webinar with Jihane Farrell follow-up + recording
HealthyLongevity.guide
Longevity
Lifestyle
Diagnostics

Harnessing the power of social connections for your client’s longevity - Webinar with Jihane Farrell follow-up + recording

Social connectedness can predict longevity: it was found to be the foremost contributor to a longer life. Learn more about how to improve your clients and patiens social support network.

Ehab Naim, MBA.
May 20, 2022
Article
Article
Effect of loneliness on longevity: Pre- and post-COVID-19 updates
Prevention
Diagnostics
Technology
Aging
Lifestyle

Effect of loneliness on longevity: Pre- and post-COVID-19 updates

People who are socially connected tend to live longer, loneliness has been linked to many diseases. During the covid pandemic, severe loneliness increased from 6% to 21%

Ehab Naim, MBA.
May 19, 2022
Article
Article
Simple lifestyle modifications can protect the brain from the effects of aging - 4 tips on how to reverse the cognitive decline
Aging
Medicine
Disease
Supplements
Nutrition

Simple lifestyle modifications can protect the brain from the effects of aging - 4 tips on how to reverse the cognitive decline

By implementing simple lifestyle changes: diet, physical activity, social interaction, and continuous learning and engagement in mental activities, supported by low stress levels.

Erik Nelson
May 18, 2022
News
News
DNA methylation signature connects chronic inflammation and diseases
Aging
Metabolism
Longevity
Diagnostics
Interventions

DNA methylation signature connects chronic inflammation and diseases

The researchers developed a clinically applicable risk score associated with weight, BMI, type 2 diabetes, coronary disease, and several other inflammation markers.

Olena Mokshyna, PhD.
May 16, 2022
News
News
Promising study: Improving longevity via microbiome transplant in mice
Body
Nutrition
Longevity
Aging

Promising study: Improving longevity via microbiome transplant in mice

The microbiota transfer from aged donors to young mice accelerated age-related decline in function. On the contrary, microbiota transfer from young to old mice resulted in opposite effects.

Ehab Naim, MBA.
May 16, 2022
Article
Article
Preventative genetic screening – single gene, genetic panel, or whole-genome?
Prevention
Diagnostics
Disease
Longevity
Metabolism

Preventative genetic screening – single gene, genetic panel, or whole-genome?

Genome and exome sequencing are anticipated to become the main diagnostic tool to detect and prevent genetic conditions with high heterogeneity (having many candidate genes).

Olena Mokshyna, PhD.
May 12, 2022
Article
Article
Longevity interventions: Current and future options
Longevity
Nutrition
Pharmaceuticals
Supplements
Medicine

Longevity interventions: Current and future options

The available data that exist on human longevity suggests that exercise and a healthy diet are major factors when it comes to reaching the ages of 80-85. What would be the options in the future?

Victor Björk
May 11, 2022
News
News
Brisk walk to live long
Lifestyle
Longevity
Aging
Metabolism

Brisk walk to live long

The authors concluded that a higher walking pace might be associated with longer LTL, shedding some light on the benefits of activities like brisk walking.

Ehab Naim, MBA.
May 11, 2022
News
News
Rapamycin, caloric restriction, or both – choose the right weapon against muscle aging
Longevity
Prevention
Nutrition
Pharmaceuticals
Body

Rapamycin, caloric restriction, or both – choose the right weapon against muscle aging

A comparison of rapamycin and caloric restriction treatments confirmed different influences on the attenuation of muscle mass loss and glucose intake.

Olena Mokshyna, PhD.
May 11, 2022
News
News
Gut microbiome and extreme longevity: an in-depth study of Hainan centenarians
Body
Longevity
Metabolism
Diagnostics

Gut microbiome and extreme longevity: an in-depth study of Hainan centenarians

The gut microbiome of the Hainan centenarians significantly differed from those of ordinary adults from the same region.

Olena Mokshyna, PhD.
May 9, 2022
Article
Article
Starting with longevity medicine for medical practitioners
Diagnostics
Interventions
Longevity
Medicine
Pharmaceuticals

Starting with longevity medicine for medical practitioners

The area of longevity medicine encompasses biomarkers of aging, implementing and assessing longevity interventions from lab data, and monitoring efficacy by the treating physician.

Victor Björk
May 4, 2022
Article
Article
From mitochondria to inflammation: mechanisms of brain aging
Metabolism
Aging
Medicine
Disease
Prevention

From mitochondria to inflammation: mechanisms of brain aging

Mechanisms related to brain aging include mitochondrial dysfunction, oxidative stress, lysosomal dysregulation, inflammation, defective stress response.

Ehab Naim, MBA.
May 2, 2022
Article
Article
How to Optimize Protein Intake for Longevity?
Nutrition
Longevity
Body
Aging
Lifestyle

How to Optimize Protein Intake for Longevity?

All clients interested in longevity should be encouraged to opt for plant-based sources of protein in place of animal ones to mimic protein restriction.

Jiří Kaloč
Apr 29, 2022
Video
Video
Is high or low IGF1 signalling better for longevity? (VIDEO)
Longevity
Medicine
Diagnostics
Body
Aging

Is high or low IGF1 signalling better for longevity? (VIDEO)

The IGF-1 pathway is involved in response to nutrients and growth factors. We will examine the signalling pathway further, see how it is activated and what processes it regulates.

Eleanor Sheekey
Apr 27, 2022
News
News
Physical activity in older adults protects brain integrity
Lifestyle
Body

Physical activity in older adults protects brain integrity

The study on cognitively intact older adults aged 65 years revealed that higher levels of physical activity corresponded with higher grey matter volume.

Ehab Naim, MBA.
Apr 25, 2022
News
News
Aerobic exercises and the MIND diet promote cognitive health in postmenopausal women
Longevity
Lifestyle
Interventions
Nutrition
Prevention

Aerobic exercises and the MIND diet promote cognitive health in postmenopausal women

The study on 68 women in the postmenopausal stage suffering from mild cognitive impairment showed that moderate-intensity exercise with the MIND diet improved the overal state and cognitive functions,

Olena Mokshyna, PhD.
Apr 25, 2022
News
News
Can contact with nature lower the preterm birth risk?
Lifestyle
Disease
Metabolism
Aging

Can contact with nature lower the preterm birth risk?

Numerous studies indicate that spending time in a forest could be beneficial for health in the case of cardiovascular disease, mental health - and also for preterm birth risk.

Agnieszka Szmitkowska, Ph.D.
Apr 25, 2022
Video
Video
Stress - how to measure and treat the silent killer of today: Follow-up of the round table discussion
HealthyLongevity.guide
Aging
Diagnostics
Interventions
Longevity

Stress - how to measure and treat the silent killer of today: Follow-up of the round table discussion

The heart rate variability (HRV) was discussed as a valuable, accessible tool to measure stress. Our speakers viewed it as a useful physiological biomarker to measure stress and aging.

Ehab Naim, MBA.
Apr 25, 2022
News
News
A new rejuvenation technique that potentially could reverse 30 years of aging!
Aging
Diagnostics
Longevity
Metabolism
Disease

A new rejuvenation technique that potentially could reverse 30 years of aging!

The researchers were able to reverse the effects of aging on dermal fibroblasts. Their results indicated that the rejuvenation effect on the transcriptome was about 30 years.

Ehab Naim, MBA.
Apr 25, 2022
Article
Article
Metabolic syndrome: a puppeteer of multiple diseases
Medicine
Disease
Metabolism
Diagnostics
Body

Metabolic syndrome: a puppeteer of multiple diseases

Metabolic syndrome (MtS) presents a constellation of symptoms. Lifestyle changes, such as physical activity, a healthy diet, and abstaining from harmful habits, are the key to fighting it.

Dr. Ana Baroni MD. Ph.D.
Apr 24, 2022
News
News
Bipolar disorder linked to accelerated cellular aging in young adults
Prevention
Disease
Medicine
Diagnostics
Metabolism

Bipolar disorder linked to accelerated cellular aging in young adults

In a study on 130 individuals with bipolar disorder, most showed a characteristic pattern of accelerated cellular aging.

Olena Mokshyna, PhD.
Apr 17, 2022
Video
Video
AMPK signalling pathway
Metabolism
Longevity
Pharmaceuticals
Aging
Disease

AMPK signalling pathway

A reduction in ATP (energy currency of a cell) activates the AMPK signalling pathway.

Eleanor Sheekey
Apr 16, 2022
Article
Article
Abdominal obesity and metabolic syndrome: A cause and consequence affecting the lifespan
Disease
Medicine
Metabolism
Longevity
Lifestyle

Abdominal obesity and metabolic syndrome: A cause and consequence affecting the lifespan

Waist circumference, even with normal body mass index, is a risk factor for metabolic syndrome.

Jiří Kaloč
Apr 15, 2022
Article
Article
Sarconeos: Nature’s solution to age-related muscle degeneration
Disease
Medicine
Metabolism
Body
Pharmaceuticals

Sarconeos: Nature’s solution to age-related muscle degeneration

Results from clinical studies demonstrate promising outcomes for the use of Sarconeos in sarcopenia.

Ehab Naim, MBA.
Apr 15, 2022
Article
Article
Resilience – a key to tackling chronic stress
Aging
Lifestyle
Longevity
Prevention
Interventions

Resilience – a key to tackling chronic stress

Resilience resources are psychological, social, and economic characteristics that help increase our resistance to stress

Erik Nelson
Apr 15, 2022
Article
Article
Slow killer: how chronic stress impairs our ability to thrive and live longer
Aging
Lifestyle
Prevention
Body
Medicine

Slow killer: how chronic stress impairs our ability to thrive and live longer

Chronic stress increases the risk of developing multiple diseases, and can shorten both health- and lifespan.

Dr. Ana Baroni MD. Ph.D.
Apr 15, 2022
News
News
Can epigenetic clock acceleration be linked to cancer? Searching for causality
Diagnostics
Disease
Aging
Body
Longevity

Can epigenetic clock acceleration be linked to cancer? Searching for causality

Genetically predicted GrimAge acceleration increased the risk of colorectal cancer in males and females.

Ehab Naim, MBA.
Apr 15, 2022
Article
Article
Muscle degeneration: a consequence of the aging process that impacts the quality of life
Disease
Aging
Diagnostics
Metabolism
Body

Muscle degeneration: a consequence of the aging process that impacts the quality of life

Primary sarcopenia is characterized by a decline in muscle mass and strength. How can your clients reduce its impact?

Ehab Naim, MBA.
Apr 13, 2022
Article
Article
Hydration - the real fountain of youth
Nutrition
Metabolism
Lifestyle
Disease
Prevention

Hydration - the real fountain of youth

Proper hydration can significantly contribute to longevity through disease risk mitigation.

Jiří Kaloč
Apr 13, 2022
Video
Video
The NF-KB pathway (VIDEO)
Medicine
Metabolism
Nutrition
Aging
Disease

The NF-KB pathway (VIDEO)

The NF-KB pathway is a key pathway involved in regulating the activation and response of inflammation.

Eleanor Sheekey
Apr 9, 2022
Article
Article
Genomic instability: a force behind aging and cancer
Aging
Longevity
Prevention
Diagnostics
Disease

Genomic instability: a force behind aging and cancer

Aging and cancer are strongly connected to genomic instability and the accumulation of harmful mutations in cells.

Olena Mokshyna, PhD.
Apr 9, 2022
Article
Article
Nature's way of promoting longevity - vitamins, polyphenols, and other natural geroprotectors
Supplements
Pharmaceuticals
Longevity
Interventions
Metabolism

Nature's way of promoting longevity - vitamins, polyphenols, and other natural geroprotectors

Natural products, like vitamins and minerals, have been shown to upregulate autophagy and influence the lifespan.

Ehab Naim, MBA.
Apr 6, 2022
Article
Article
Glucose and insulin: The key players in longevity plus 6 tips to improve their levels
Metabolism
Medicine
Disease
Longevity
Technology

Glucose and insulin: The key players in longevity plus 6 tips to improve their levels

Glucose dysregulation (increase or decrease) is responsible for developing many conditions shortening the lifespan.

Ehab Naim, MBA.
Apr 4, 2022
Video
Video
Microbiome testing and gut microbiomics (VIDEO)
Body
Diagnostics
Supplements
Interventions

Microbiome testing and gut microbiomics (VIDEO)

What is the therapeutic potential in analysing ones microbiome to see how interventions could improve health?

Eleanor Sheekey
Apr 4, 2022
News
News
Can lifestyle affect dementia? Results from a study on Indigenous people of Bolivia
Disease
Lifestyle
Metabolism
Body
Aging

Can lifestyle affect dementia? Results from a study on Indigenous people of Bolivia

Tsimane and Moseten Amerindians have one of the lowest number of dementia cases worldwide, and the cases are mild.

Ehab Naim, MBA.
Apr 3, 2022
News
News
Fasting mimicking diet - a new weapon against prostate cancer?
Body
Disease
Lifestyle
Interventions
Nutrition

Fasting mimicking diet - a new weapon against prostate cancer?

Study results prove that fasting mimicking diet may be used in prostate cancer pacients and as a preventive measure.

Agnieszka Szmitkowska, Ph.D.
Apr 3, 2022
Video
Video
Healthy longevity approach in health coaching (Webinar with Erik Nelson follow-up + recording)
HealthyLongevity.guide
Longevity
Lifestyle
Interventions

Healthy longevity approach in health coaching (Webinar with Erik Nelson follow-up + recording)

Erik Nelson mentioned several approaches related to nutrition, physical activity, and more.

Ehab Naim, MBA.
Apr 1, 2022
Article
Article
Working in a stressful environment can shorten your life — workplace wellness programs
Longevity
Lifestyle
Body
Aging
Metabolism

Working in a stressful environment can shorten your life — workplace wellness programs

Mental stress and long work hours increase mortality by about 20% - occupational stress accelerates epigenetic aging.

Ehab Naim, MBA.
Mar 29, 2022
Article
Article
Light therapies for regeneration, rejuvenation, and healing
Interventions
Disease
HealthyLongevity.guide
Prevention
Lifestyle

Light therapies for regeneration, rejuvenation, and healing

Light therapies present a range of safe methods that show their clinical potential against many conditions.

Erik Nelson
Mar 29, 2022
News
News
One drop won’t hurt: A new research shows how brain changes under light and moderate alcohol consumption
Body

One drop won’t hurt: A new research shows how brain changes under light and moderate alcohol consumption

A negative relationship between alcohol intake and gray and white matter measures was generally observed.

Olena Mokshyna, PhD.
Mar 29, 2022
News
News
MondoA as a regulator of cellular senescence and mitochondrial homeostasis
Longevity
Disease
Aging
Interventions

MondoA as a regulator of cellular senescence and mitochondrial homeostasis

Retained MondoA activity delays cellular senescence through promoting autophagy.

Ehab Naim, MBA.
Mar 29, 2022
News
News
Choir singing reduces depressive symptoms in patients with dementia
Interventions
Disease

Choir singing reduces depressive symptoms in patients with dementia

Music interventions are promising and possibly cost-effective non-pharmacological approaches for people with dementia.

Agnieszka Szmitkowska, Ph.D.
Mar 22, 2022
News
News
Human lifespan and genes: new insights from the UK Biobank exome study
Longevity
Diagnostics

Human lifespan and genes: new insights from the UK Biobank exome study

A study of gene variants connected with longevity was performed on an unprecedented dataset of over 500,000 participants

Olena Mokshyna, PhD.
Mar 17, 2022
News
News
Multi-omics data unraveled 9 aging clocks for specific organs and systems
Diagnostics
Aging

Multi-omics data unraveled 9 aging clocks for specific organs and systems

The application of the multi-omics-based organ-specific aging clocks could be the future of preventative medicine.

Agnieszka Szmitkowska, Ph.D.
Mar 15, 2022
News
News
Calorie restriction in humans: results after 2-years CALORIE study
Longevity
Prevention
Body
Medicine

Calorie restriction in humans: results after 2-years CALORIE study

Calorie restriction extends the healthspan thanks to improving thymus funcions and adipose tissue reprogramming.

Olena Mokshyna, PhD.
Mar 12, 2022
Article
Article
Restoring vision with gene therapy: Shedding the light on LUMEVOQ®
Disease
Metabolism
Interventions

Restoring vision with gene therapy: Shedding the light on LUMEVOQ®

LUMEVOQ® or (GS010) is a gene therapy that has been tested as a treatment for Leber hereditary optic neuropathy (LHON).

Ehab Naim, MBA.
Mar 12, 2022
News
News
Four to seven minutes of muscle-strengthening activities per day may reduce the risk of death, cancer, and other diseases
Longevity
Lifestyle
Interventions
Disease

Four to seven minutes of muscle-strengthening activities per day may reduce the risk of death, cancer, and other diseases

Muscle-strengthening exercises were associated with a 12% reduction in the risk of developing cancer.

Ehab Naim, MBA.
Mar 11, 2022
News
News
The connection between the cystine/glutamate antiporter system and life extension in mice
Body
Aging
Disease
Metabolism

The connection between the cystine/glutamate antiporter system and life extension in mice

Targeting the cystine/glutamate antiporter system xc- is a promising strategy to promote healthy aging.

Agnieszka Szmitkowska, Ph.D.
Mar 11, 2022
Article
Article
The scourge of malnutrition: causes and consequences
Diagnostics
Aging
Longevity
Medicine
Body

The scourge of malnutrition: causes and consequences

Malnutrition is a dangerous condition that influences both growing and aging.

Olena Mokshyna, PhD.
Mar 9, 2022
Article
Article
Epigenetic alterations: Small changes affecting health and longevity
Diagnostics
Aging
Longevity
Disease

Epigenetic alterations: Small changes affecting health and longevity

DNA methylation, histone modifications, or microRNA expression are among the most well-established epigenetic alteration

Victor Björk
Mar 9, 2022
Video
Video
“How nutritionists can make an impact in pursuit of longevity” - Webinar recording
HealthyLongevity.guide
Nutrition

“How nutritionists can make an impact in pursuit of longevity” - Webinar recording

Nutritionist Jiří Kaloč discussed nutrition's impact on lowering the risk of diseases and prolonging the lifespan.

Ehab Naim, MBA.
Mar 8, 2022
News
News
A history of mental diseases increases the risk of dementia: Results from a 3-decade analysis
Body
Disease
Longevity
Medicine

A history of mental diseases increases the risk of dementia: Results from a 3-decade analysis

Individuals with mental disorders were more likely to develop dementia than those without mental illnesses.

Ehab Naim, MBA.
Mar 7, 2022
Video
Video
Nutrigenomics (VIDEO)
Prevention
Nutrition
Lifestyle
Interventions
Diagnostics

Nutrigenomics (VIDEO)

Nutrigenomics studies the relationship between the human genome, human nutrition and health

Eleanor Sheekey
Mar 2, 2022
Article
Article
How to fine-tune plant-based diets for longevity
Metabolism
Nutrition
Diagnostics
Supplements

How to fine-tune plant-based diets for longevity

Plant-based protein is an excellent choice for longevity, and the overall protein quantity should be increased with age.

Jiří Kaloč
Mar 2, 2022
Article
Article
NAD+ : The healthy aging molecule
Metabolism
Longevity
Supplements

NAD+ : The healthy aging molecule

NAD+ is so important to our health because it acts as a regulator of so many important cellular pathways.

Dr. Nichola Conlon from Nuchi
Mar 2, 2022
News
News
Hydrogen sulfide may contribute to longevity: Results from a preclinical study on C. elegans
Aging
Longevity
Nutrition

Hydrogen sulfide may contribute to longevity: Results from a preclinical study on C. elegans

Results of their experiments revealed that ATF-4 influences longevity through hydrogen sulfide (H2S) production.

Ehab Naim, MBA.
Mar 2, 2022
News
News
Healthier Americans tend to use mobile health apps more
Medicine
Disease
Technology

Healthier Americans tend to use mobile health apps more

Users reporting excellent, or good health were more likely to use health apps than those in fair or poor health.

Agnieszka Szmitkowska, Ph.D.
Mar 2, 2022
Article
Article
Hallmarks of health: Understanding the factors that contribute to health and wellness
Lifestyle
Body
Prevention
Aging
Disease

Hallmarks of health: Understanding the factors that contribute to health and wellness

Hallmarks of health include the integrity of barriers, response to stressors, hormetic regulation, repair and regeration

Ehab Naim, MBA.
Mar 1, 2022
News
News
Are older people slower thinkers? New study shows that mental speed remains high until 60
Lifestyle
Body
Prevention
Diagnostics

Are older people slower thinkers? New study shows that mental speed remains high until 60

For large parts of the human lifespan and work careers mental speed remains mostly stable. 

Olena Mokshyna, PhD.
Feb 28, 2022
News
News
Can senolytics influence frailty? Shedding light on preclinical study results
Longevity
Pharmaceuticals
Supplements
Aging
Body

Can senolytics influence frailty? Shedding light on preclinical study results

The authors concluded that dasatinib and quercetin might possess protective properties against frailty.

Ehab Naim, MBA.
Feb 25, 2022
Article
Article
Mitochondria-based therapeutics: perspectives and first CohBar clinical trials
Metabolism
Medicine
Disease
Body

Mitochondria-based therapeutics: perspectives and first CohBar clinical trials

The preliminary results on the safety and efficacy of MDPs give hope for further development of anti-aging science.

Olena Mokshyna, PhD.
Feb 25, 2022
Article
Article
DNL 151 - LRRK2 protein inhibitor for Parkinson's disease treatment
Disease
Aging
Medicine
Pharmaceuticals
Metabolism

DNL 151 - LRRK2 protein inhibitor for Parkinson's disease treatment

The preclinical studies presented that reduction of LRRK2 activity or expression is neuroprotective.

Agnieszka Szmitkowska, Ph.D.
Feb 25, 2022
Article
Article
What is neuroplasticity and how it works?
Body
Prevention
Metabolism
Lifestyle
Aging

What is neuroplasticity and how it works?

By employing learning, humans can live in a healthier and more fulfilled way and delay age-related cognitive decline.

Olena Mokshyna, PhD.
Feb 25, 2022
News
News
The link between oxidative stress and lifespan in Daphnia pulex
Prevention
Metabolism
Longevity
Diagnostics

The link between oxidative stress and lifespan in Daphnia pulex

What is the correlation between the naturally occurring sequence variations in ND5 and the lifespan in Daphnia?

Agnieszka Szmitkowska, Ph.D.
Feb 24, 2022
News
News
Suppression of mitochondrial protein import as a new longevity mechanism
Metabolism
Longevity
Diagnostics
Nutrition

Suppression of mitochondrial protein import as a new longevity mechanism

A new study has tested reducing the mitochondrial load as a possible longevity intervention.

Olena Mokshyna, PhD.
Feb 24, 2022
News
News
Natural disasters can accelerate aging: A new study on non-human primates
Aging
Longevity
Disease

Natural disasters can accelerate aging: A new study on non-human primates

Natural disasters tend to induce differences in immune cell gene expression similar to those of the natural aging.

Ehab Naim, MBA.
Feb 23, 2022
News
News
Vitamin D and marine omega-3 fatty acids positively affect autoimmune disease incidence.
Supplements
Nutrition
Disease

Vitamin D and marine omega-3 fatty acids positively affect autoimmune disease incidence.

Vitamin D supplementation for five years, with or without omega-3, decreased autoimmune disease by 22%.

Agnieszka Szmitkowska, Ph.D.
Feb 23, 2022
Article
Article
Make healthy aging and longevity your niche as a nutritionist
Longevity
Diagnostics
Interventions
Nutrition
Medicine

Make healthy aging and longevity your niche as a nutritionist

Healthy aging is rapidly gaining in popularity and nutritionists are well placed to capitalize on this trend.

Jiří Kaloč
Feb 22, 2022
News
News
​​Selenium and exercise: new insights into the hippocampal neurogenesis
Supplements
Prevention
Metabolism
Body

​​Selenium and exercise: new insights into the hippocampal neurogenesis

Aging has been associated with a natural decline in selenium status.

Olena Mokshyna, PhD.
Feb 21, 2022
News
News
A protein that links hypertension and diabetes has been found
Disease
Metabolism

A protein that links hypertension and diabetes has been found

Scientists suggested the role of the activation of carotid body in homeostatic response to high blood glucose levels.

Agnieszka Szmitkowska, Ph.D.
Feb 17, 2022
Article
Article
Minerals: The catalysts of metabolism and bodily functions
Nutrition
Longevity
Prevention
Body
Metabolism

Minerals: The catalysts of metabolism and bodily functions

Minerals impact the lifespan due to their role in many enzymatic and metabolic functions. 

Dr. Ana Baroni MD. Ph.D.
Feb 16, 2022
Article
Article
The multiomics – a precision approach for aging measurement
Diagnostics
Interventions

The multiomics – a precision approach for aging measurement

Multiomics analyses data are integrated from multiple specific fields or "omes": genome, transcriptome, and proteome.

Agnieszka Szmitkowska, Ph.D.
Feb 15, 2022
Article
Article
Artificial intelligence and machine learning
Interventions
Disease
Diagnostics
Aging
Longevity

Artificial intelligence and machine learning

Modern machine learning-based AI shows great promises in the medical field, particularly for tracking healthy aging.

Olena Mokshyna, PhD.
Feb 15, 2022