The cardiometabolic diseases were independently associated with the risk of dementia and visible brain imaging differences far more than was a genetic risk.
Psychosocial stress potentially contributes to accelerated immune aging. This is important because immune aging plays a role in multiple chronic conditions and the aging process itself.
The aging process causes a decline in the overall body function. There are physiological parameters that could help establish how far aging has impacted the body to capture these changes.
Fisetin, a bioactive compound found in edible plants, is reported to have a number of biological activities, including antioxidant, antimicrobial, anticancer, antidiabetic, and other properties
Dr. Owen Phillips is a neuroscientist and a founder and CEO of BrainKey – an AI and neuroscience startup. We spoke about neuroscience, aging, and the brain's longevity.
Nicotinamide mononucleotide (NMN) is a direct precursor to NAD+, a critical coenzyme found in every cell in your that is involved in hundreds of metabolic processes and its levels decline with age.
J147 is a promising drug candidate against Alzheimer’s disease – an illness that affects millions but still lacks reliable therapeutics. J147 may also acts as geroprotector.
When a hematopoietic stem cell starts making copies with the same genetic mutation, molecular damage accumulates. This causes abrupt changes in tissue composition due to clonal structure alterations.
As individuals age, the GIT function and structure begin to deteriorate. These adverse effects could be attenuated by utilizing approaches like controlling dietary components to promote gut health.
Cellular senescence is one of the nine aging hallmarks with the negative impact but also with good aspects, including wound healing, fibrotic tissue resolution, limb patterning...
Alzheimer's disease (AD) is a debilitating neurodegenerative condition causing cognitive and psychiatric problems. Diagnosis is complicated, and no disease-modifying therapy is available at the moment
Telomere shortening is itself a cause of aging, but telomeres also shorten in response to stresses and diseases. Extending telomeres in animals prolongs their lifespan, albeit modestly.
There are several key aspects of the traditional Okinawa diet that can be connected to health and longevity: calorie restriction, high antioxidants intake, low sugar and fat intake.
Social connectedness can predict longevity: it was found to be the foremost contributor to a longer life. Learn more about how to improve your clients and patiens social support network.
People who are socially connected tend to live longer, loneliness has been linked to many diseases. During the covid pandemic, severe loneliness increased from 6% to 21%
By implementing simple lifestyle changes: diet, physical activity, social interaction, and continuous learning and engagement in mental activities, supported by low stress levels.
The researchers developed a clinically applicable risk score associated with weight, BMI, type 2 diabetes, coronary disease, and several other inflammation markers.
The microbiota transfer from aged donors to young mice accelerated age-related decline in function. On the contrary, microbiota transfer from young to old mice resulted in opposite effects.
Genome and exome sequencing are anticipated to become the main diagnostic tool to detect and prevent genetic conditions with high heterogeneity (having many candidate genes).
The available data that exist on human longevity suggests that exercise and a healthy diet are major factors when it comes to reaching the ages of 80-85. What would be the options in the future?
A comparison of rapamycin and caloric restriction treatments confirmed different influences on the attenuation of muscle mass loss and glucose intake.
The area of longevity medicine encompasses biomarkers of aging, implementing and assessing longevity interventions from lab data, and monitoring efficacy by the treating physician.
The IGF-1 pathway is involved in response to nutrients and growth factors. We will examine the signalling pathway further, see how it is activated and what processes it regulates.
The study on 68 women in the postmenopausal stage suffering from mild cognitive impairment showed that moderate-intensity exercise with the MIND diet improved the overal state and cognitive functions,
Numerous studies indicate that spending time in a forest could be beneficial for health in the case of cardiovascular disease, mental health - and also for preterm birth risk.
The heart rate variability (HRV) was discussed as a valuable, accessible tool to measure stress. Our speakers viewed it as a useful physiological biomarker to measure stress and aging.
The researchers were able to reverse the effects of aging on dermal fibroblasts. Their results indicated that the rejuvenation effect on the transcriptome was about 30 years.
Metabolic syndrome (MtS) presents a constellation of symptoms. Lifestyle changes, such as physical activity, a healthy diet, and abstaining from harmful habits, are the key to fighting it.