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Brisk walk to live long
The authors concluded that a higher walking pace might be associated with longer LTL, shedding some light on the benefits of activities like brisk walking.
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Walking is a form of physical activity available to people of all ages. It is an activity that benefits individuals on physical, mental, and social levels and has little to no adverse effects. Research has highlighted that walking was associated with reduced cardiovascular disorders and related mortality. Moreover, brisk walkers were found to add 20 years to their lives compared to slow walkers. This was validated by results from the UK Biobank, which found that 10 minutes of brisk walking per day was linked to longer life expectancy.
Previous research has indicated that higher physical activity levels were associated with longer leukocyte telomere length (LTL). Telomeres are DNA-protein complexes that protect chromosome ends from degradation and genomic instability. The DNA component of the telomere decreases with every cell cycle until reaching cellular senescence. Factors like oxidative stress and inflammation also influence telomere shortening. LTL is used as a marker for telomere length in other tissues.
Much of the available literature supporting the link between higher physical activity and slower biological aging in humans involves observational and/or small sample size studies. Also, there is insufficient amount of research on the connection between LTL and brisk walking. To address this, Dempsey et al. sought to investigate the association between self-reported walking pace and LTL in middle-aged adults. The researchers used a sample comprising over 405,000 participants from the UK Biobank. Physical activity was measured using a wrist-mounted accelerometer.
Results revealed that average and brisk walkers had significantly longer LTL compared to slow walkers. Further analysis highlighted that a greater proportion of daily physical activity at a higher intensity was linked with longer LTL. Evidence from this study supports the importance of walking pace in determining the overall health of humans.
The authors concluded that a higher walking pace might be associated with longer LTL, shedding some light on the benefits of activities like brisk walking. They highlighted the need for further research to understand the influence of higher intensity physical activity on LTL erosion.
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Walking is a form of physical activity available to people of all ages. It is an activity that benefits individuals on physical, mental, and social levels and has little to no adverse effects. Research has highlighted that walking was associated with reduced cardiovascular disorders and related mortality. Moreover, brisk walkers were found to add 20 years to their lives compared to slow walkers. This was validated by results from the UK Biobank, which found that 10 minutes of brisk walking per day was linked to longer life expectancy.
Previous research has indicated that higher physical activity levels were associated with longer leukocyte telomere length (LTL). Telomeres are DNA-protein complexes that protect chromosome ends from degradation and genomic instability. The DNA component of the telomere decreases with every cell cycle until reaching cellular senescence. Factors like oxidative stress and inflammation also influence telomere shortening. LTL is used as a marker for telomere length in other tissues.
Much of the available literature supporting the link between higher physical activity and slower biological aging in humans involves observational and/or small sample size studies. Also, there is insufficient amount of research on the connection between LTL and brisk walking. To address this, Dempsey et al. sought to investigate the association between self-reported walking pace and LTL in middle-aged adults. The researchers used a sample comprising over 405,000 participants from the UK Biobank. Physical activity was measured using a wrist-mounted accelerometer.
Results revealed that average and brisk walkers had significantly longer LTL compared to slow walkers. Further analysis highlighted that a greater proportion of daily physical activity at a higher intensity was linked with longer LTL. Evidence from this study supports the importance of walking pace in determining the overall health of humans.
The authors concluded that a higher walking pace might be associated with longer LTL, shedding some light on the benefits of activities like brisk walking. They highlighted the need for further research to understand the influence of higher intensity physical activity on LTL erosion.
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Dr. Ana Baroni MD. Ph.D.
Scientific & Medical Advisor
Quality Garant
Ana has over 20 years of consultancy experience in longevity, regenerative and precision medicine. She has a multifaceted understanding of genomics, molecular biology, clinical biochemistry, nutrition, aging markers, hormones and physical training. This background allows her to bridge the gap between longevity basic sciences and evidence-based real interventions, putting them into the clinic, to enhance the healthy aging of people. She is co-founder of Origen.life, and Longevityzone. Board member at Breath of Health, BioOx and American Board of Clinical Nutrition. She is Director of International Medical Education of the American College of Integrative Medicine, Professor in IL3 Master of Longevity at Barcelona University and Professor of Nutrigenomics in Nutrition Grade in UNIR University.
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